Extraordinary extended lampbrush chromosomes with thousands of transcription loops are favorable objects in chromosome biology. Chromosomes become lampbrushy due to unusually high rate of transcription during oogenesis. However, until recently, the information on the spectrum of transcribed sequences as well as genomic context of individual chromomeres was mainly limited to tandemly repetitive elements. Here we briefly outline novel findings and future directions in lampbrush chromosome studies in the post‐genomic era. We emphasize the fruitfulness of combining genome‐wide approaches with microscopy imaging (...) techniques using lampbrush chromosomes as a remarkable model object. We believe that new data on the spectrum of sequences transcribed on the lateral loops of lampbrush chromosomes and their structural organization push the boundaries in the discussion of their biological role. Also see the video abstract here: https://youtu.be/zexoHfzX9rM. (shrink)

The subject of the research is utopian discourse, which unites all the variety of concepts related in one way or another to utopia, utopian dimension of reality and understanding of the Future (utopian element, utopian impulse, utopian optics, utopianism, utopian consciousness, utopian thinking, dystopia, etc.). Special attention is paid to the study of the explanatory and predictive potential of utopian discourse, identifying its boundaries and analysis of the relationship with ideological discourse. The conceptualization of utopian discourse is based on an (...) instrumental approach to utopia, which is complemented by the communicative approach and the interpretive concept of culture by K. Geertz, which justifies the possibility of considering utopian discourse as a semantic and symbolic matrix. The novelty of the research is to identify and substantiate the exaggerated dichotomy of thinking and otherness as the structure-forming elements of utopian discourse. This contributed to the assessment of utopian discourse as a peculiar but viable form of reflection of political reality and the construction, consolidation and comprehension of values. The proposed algorithm of thinking with dichotomies made it possible to trace the process of constructing utopian discourse on the basis of a pyramid of dichotomies, consisting of system-forming, key and peripheral dichotomies. The article clarifies that the otherness of utopian discourse is manifested in the historicity, radicality and inextricable connection of utopian discourse with the Present. The indicated specificity of utopian discourse has led to the clarification of the reasons for the negative and/or skeptical attitude towards utopia and utopian discourse, as well as to the definition of its strengths and weaknesses. The authors conclude that despite the identified shortcomings, which often lead utopias to periodic displacement from the framework of actual political life, utopian discourse can have a significant impact on the change and development of society. (shrink)

The purpose of the research is to analyze the mechanism of formation of technological competence of students of pedagogical education. The article pays special attention to the levels of technological competence, the achievement of which contributes to the acquisition of certain knowledge, skills and abilities. The article focuses on the interaction between the digitalization of society and the formation of technological competence. As a result, the main features for assessing the level of formation of technological competence were identified. It is (...) emphasized that the formation of the technological competence of students of pedagogical education presupposes the division of the process of students' research activities into a number of stages, which are considered in more detail. (shrink)

The purpose of the study is to determine the personal results of students with disabilities and to identify the necessary conditions for effective work with this category of children in distance learning. The analysis of the results revealed the need for the use of subject-oriented technology in the educational process, which contributes to the formation of the subjective position of students, allowing for the individualization of the educational process, maximally compensating for developmental deficits caused by diseases. As a result, the (...) necessity of organizing purposeful career guidance work with disabled children and educational work with parents was revealed. (shrink)

The study highlights the issues of formation and development of the system of evaluation criteria for the development of the territory in the system of effective economic management. The reliability of data collection and processing plays a dominant role in creating a reliable platform of indicators, the formation of consistent management decisions in the field of economic and social development of the territory. In the processes of socio-economic nature, the problems are considered and the factors influencing the construction of the (...) evaluation system are disclosed. In our opinion, studies of economic processes undoubtedly affect the social side of the development of the territory. As a result, an assessment of the state of affairs in the Stavropol territory is presented, but some aspects touched upon in the study require an additional information block. (shrink)

The article is devoted to the problem of justifying a uniform approach to the fundamental basic category of accounting – documentation. The relevance is due to the need for terminology to match the changes taking place in its subject of research - the economic life of an economic entity. The author conducts a comparative analysis of the interpretation of accounting reception "documentation", "documenting", based on educational publications of leading scientists, current regulatory documents in the field of management documentation. The author (...) conducts a comparative analysis of the interpretation of accounting reception "documentation", "documenting", based on educational publications of leading scientists, current regulatory documents in the field of management documentation. As a result, the author formulates the concept of "documentation", which contains features that correspond to the modern understanding of the role and significance of this accounting technique in the formation of accounting information. (shrink)

Values formed in culture, reflecting social relations, fulfilling a regulatory role, are defined as norms fixed in the culture of society. Moral norms that combine such properties of morality as normativity, imperativeness and evaluativeness act as significant foundations of culture. Values and norms enshrined in culture contribute to the integration and spiritual development of society The transformational processes taking place in modern society have influence on the value system. The relevance of this study is determined by the dialectic of emerging (...) contradictions in modern Russian culture caused by the formation of ambivalent values, norms, and attitudes in mass culture that have a negative impact on collective consciousness, on changing the value foundations of culture in modern society, which jeopardizes the safety of culture. In the focus of the analyzed problem, kitsch culture as a phenomenon of mass culture acts as the subject of research. The purpose of the study is to identify threats to cultural security coming from kitsch culture, which transforms the value foundations of culture, and to identify strategies to protect Russian culture. The study of the voiced issues is carried out through the prism of socio-cultural, structural-functional, interdisciplinary approaches. The novelty of the studied problem lies in the fact that kitsch culture acts as a pseudo-culture, which is devoid of aesthetic and artistic value and moral content, as one of the sources that creates certain risks and poses threats to cultural security. In particular, we are talking about the organization of joint activities of government agencies, public organizations, scientific, cultural and educational spheres, based on the principles of optimizing the constructive impact on the consciousness of the younger generation through the mediation process and inculturation. (shrink)

The subject of the research is the concept of "Russian idea" from the point of view of its transformation in the conditions of the modern postmodern paradigm. The characteristic markers forming the modern cultural-historical and philosophical paradigm are revealed – the specifics of their influence on the concept of "Russian idea" are analyzed. An example of the modern representation of the "neo-Eurasian" version of the concept as interpreted by A. G. Dugin demonstrates how in a postmodern situation, even ideas that (...) are in discursive opposition to postmodern principles inevitably turn out to be embedded in the modern paradigm. Russian postmodern situation determines the specific forms of existence of the concept of "Russian idea", which, in turn, are representative for the analysis of phenomena, processes and transformations of modern Russian culture and the study of its dynamics. The novelty of the research lies in the analysis of the "Russian idea" as a concept with an unchanging semantic core, fixed through the presence of cross–cutting terms, as well as in identifying the characteristic types of modern forms of existence of the concept - Messianic, conservative-protective, nationalist, neo-Eurasian, political-ideological, liberal and others. The article analyzes and identifies the patterns of the constitution of the concept "Russian idea" in the conditions of the postmodernist paradigm, examines the specific markers characterizing the concept in the postmodern situation. The "Russian idea", on the one hand, is opposed to postmodernism as an axiological antinomy, on the other hand, modern markers of the concept are revealed, making it part of the postmodern system. (shrink)

The article deals with the problematization of the study of the kon (unwritten rules) phenomenon. The functions of the unwritten rules (kon) are compared with the functions of the law. The constitution of social reality as a socio-historical process that establishes the basic categories of society's perception of its social existence is the object of research. The subject of the study is the poorly studied functions of the “kon” in the constitution of social reality. The methodology is held together by (...) general theoretical methods of typology and comparison. The study is built from the observation of the historical phenomenon of the horse to the disclosure of the heuristic potential of the concept of “kon” for describing the phenomena of modern life. The basis of the methodology is the theory of binary oppositions of culture by A.S. Akhiezer, reinforced the dialectical-dialogical pragmatic model of metacommunication R.T. Craig. The social functions of the horse remain poorly studied due to a certain way of configured research optics, concentrated on the laws governing the control of a single center of power by a poorly organized periphery. (shrink)

Purpose: The main purpose of this article is to show that the paradigm of viewing the ‘hard problem’ of consciousness in analytic philosophy makes it a pseudo-problem rather than a ‘hard problem’. The objectives of this research included showing the reasons for the authors’ thesis, demonstrating the irreducibility of consciousness as a special layer of reality, and proposing a way to overcome these difficulties. Design/methodology/approach: In this article, the ‘hard problem’ of consciousness is viewed from the standpoints of the transcendental-phenomenological (...) and dialectical approaches and is analyzed through the prism of the principle of onto-gnoseological uncertainty. Findings: It is shown that the way of formulating the ‘hard problem’ in the analytical philosophical tradition inevitably makes it a pseudo-problem. At the same time, with the consistent realization of the principle of onto-gnoseological uncertainty, the antinomy of solutions to the problems of consciousness is eliminated, which opens up a way to a productive solution of problems related to the interpretation of consciousness both in natural sciences and in philosophy. Originality/value : This research reveals the methodological potential of applying the principle of onto-gnoseological uncertainty to the problems that arise in modern philosophy in connection with the achievements of natural sciences. (shrink)

The author demonstrates the new thesis about the space of the moral that is parallel to law. The moral does not act automatically by itself. In legally meaningful situations, the moral often remains neutral, becomes kind of paralyzed, and demonstrates its weakness, leaving the person face to face with the strikes of immorality. Powerful impulse of the moral of the XXI century relates to the resolution of its unconventional problems.

The modernizing global world with new sociocultural practices actualizes the study of creativity as a constitutive phenomenon of human personality in the context of the challenges of modern era. The object of this research is creativity as a cultural phenomenon. The subject is creativity in the S. Freud's concept of psychoanalysis. In the era of change and uncertainty, when the role of creativity is increasing, the ideas of S. Freud acquire special significance. The article considers the unconscious in the context (...) of the social, in correlation with social factors and as a key position in creativity. The theoretical and methodological framework of the study includes cultural-historical and comparative methods. The systemic approach allowed viewing the phenomenon of creativity as a system in combibation of elements. The author also used the methods of analogy, analysis, comparison, and generalization. The discovered by Freud mechanism of sublimation is considered through the lens of creativity, as a way of redirecting energy displaced into the field of the unconscious by social factors, the sphere of creativity. The psychoanalytic concept serves as the methodological basis for explaining creativity as a complex process in combination of the conscious and unconscious. (shrink)

The purpose of the study is to identify promising opportunities for outsourcing business processes of an enterprise in the context of the COVID-19 pandemic. The scientific novelty lies in the fact that the article substantiates the possibilities of outsourcing business processes. As a result, it was found that today the global COVID-19 pandemic has forced companies to look for new ways to manage their enterprises, and outsourcing, having great advantages, provides many opportunities for this. It is concluded that enterprises will (...) face huge changes in the short term and must adapt today in order to continue to achieve their initial strategic goals based on the use of business process outsourcing. (shrink)

The purpose of the study is to assess changes in Russian legislation and legislative initiatives related to cryptocurrencies and digital financial assets. The article focuses on the possible economic consequences of using cryptocurrency for Russian business; determining the degree of impact of transactions with digital assets on the country's economy in connection with the introduction of the Federal Law of the Russian Federation regarding cryptocurrency. The scientific novelty lies in the development and theoretical justification of the legal principles of regulation (...) of cryptocurrency and its place in the domestic legal system, the need to improve the legislation of the Russian Federation in relation to cryptocurrency is substantiated. As a result, the existing legal framework governing the circulation of cryptocurrencies and digital assets in Russia was analyzed, measures of responsibility for failure to report on transactions with cryptocurrencies were identified, and the need to eliminate disagreements on the legalization of cryptocurrencies in the country was substantiated. (shrink)

The purpose of the study is to propose the optimal forms of practice-oriented education in relation to music specialties and areas of training at a university of arts and culture. The article focuses on the differences in the Federal state educational standards of the previous and current generations. in the part concerning the organization of practice-oriented training. The conditions for the optimization of this process are considered. The scientific novelty consists in identifying specific forms of work and specific features of (...) practice-oriented teaching of students of various musical specialties of the university. As a result of the research, effective forms of practice-oriented education have been developed, which are introduced into the process of professional training of future specialists in the field of musical art and pedagogy. (shrink)

The purpose of the study is to propose the author's approach to the complex application of strategic analysis methods based on SWOT analysis. The article discusses the well-known and presented in various sources methods of strategic analysis. Special attention is paid to SWOT-analysis, various points of view on its role are investigated. The scientific novelty lies in the determination of the logical connection between the methods of strategic analysis and SWOT-analysis and the development of the author's approach to the procedure (...) for conducting strategic analysis based on their integrated use. As a result, found that a strategic analysis of stepwise character. In this case, the result of one step of analysis simultaneously serves as the initial information for conducting another step of analysis. To systematize the information obtained during the analysis, a SWOT analysis matrix is used. (shrink)

The purpose of the study is to analyze the processes of implementing the import substitution policy, based on the use of techniques and methods of influencing participants in market relations used by public authorities, which make it possible to identify its strengths and weaknesses and build the author's vision of directions for its stabilization. The authors focus on the prevailing opinion on the phased implementation of the import substitution policy, as well as on its application as a retaliatory measure to (...) the current sanctions regimes. The analysis of scientific sources on the issues under study allows us to draw a conclusion about its special status as a tool for the development of territories. The scientific novelty of the article lies in the author's position of the reasons for the reduction in the production of the main import-substituting food products, as well as changes in the import supply of food products. As a result, the authors expressed the need to change the approaches used to stimulate the production of food products based on the principles of innovation and science. (shrink)

The purpose of the study is to reveal the features of the formation and functioning of Russian business ecosystems in modern conditions, to identify their main advantages and disadvantages, to propose ways to solve problems caused by a radical change in the digital space. The article examines the prerequisites for the emergence of business ecosystems, the features of their legal regulation, analyzes the options for organizational and technological structures, the problems of interaction of all participants in the process. Scientific novelty (...) lies in the development of theoretical provisions, the analysis of modern models that determine the organizational and technological structure of business ecosystems, the development of applied management tools and the definition of starting points for their research. As a result, the main features that characterize business ecosystems and most fully reflect their differentiation have been identified. The author's classification has been developed, the practical scope of which will allow to study the functioning of systems, both as a whole, and their individual elements, being at the same time a management tool. (shrink)

The article provides the results of a comparative study of the main theories of language and communication in the philosophical thought of the twentieth century. The authors focus on the social significance of the considered phenomena, their role in the transformation and consolidation of society. An analysis of the ideas of existentialist thinkers, analytical philosophy, the theory of communicative action by J. Habermas and others shows their relevance and practical importance for creating a universal mechanism for the development of modern (...) society based on the principles of agreement, mutual understanding and openness. (shrink)